Vitamin c dan update


















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We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. Vitamin C and Vascular Disease We and others have shown that the endothelium plays a crucial role in the pathophysiology of vascular disorders [ , , , , , , , , , , , , ]. Conclusions Both preclinical and clinical data available in the literature show that Vitamin C plays a pivotal role in a number of processes involved in the pathogenesis of CVD.

Author Contributions Data curation, writing—original draft preparation, M. Conflicts of Interest The authors declare no conflict of interest.

References 1. Kyle: R. Albert Szent-Gyorgy—Nobel laureate. Mayo Clin. Szent-Gyorgyi A. The Identification of Vitamin C. Zilva S. The Antiscorbutic Fraction of Lemon Juice. Carpenter K. The discovery of vitamin C. De Tullio M. Beyond the antioxidant: The double life of vitamin C. Frei B. Ascorbate is an outstanding antioxidant in human blood plasma.

Ascorbate: The most effective antioxidant in human blood plasma. Wyckelsma V. Jacob R. Vitamin C function and status in chronic disease. Van den Berg J. The cooperative action of vitamins E and C in the protection against peroxidation of parinaric acid in human erythrocyte membranes.

Johnston C. Vitamin C elevates red blood cell glutathione in healthy adults. Englard S. The biochemical functions of ascorbic acid. New developments and novel therapeutic perspectives for vitamin C. Carr A. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Warner M. Anemia, Iron Deficiency. Sourabh S. Blood Cells Mol. Hunt J. Effect of ascorbic acid on apparent iron absorption by women with low iron stores. Davidsson L.

Iron bioavailability studied in infants: The influence of phytic acid and ascorbic acid in infant formulas based on soy isolate. Linster C. Vitamin C. Biosynthesis, recycling and degradation in mammals. FEBS J. Drouin G. The genetics of vitamin C loss in vertebrates.

Grollman A. Enzymic synthesis of L-ascorbic acid in different animal species. Bublitz C. The enzymic conversion of L-gulonate to L-as-corbate by rat-liver enzymes.

Chatterjee I. Biological synthesis of L-ascorbic acid in animal tissues: Conversion of L-gulonolactone into L-ascorbic acid. Nishikimi M. Molecular basis for the deficiency in humans of gulonolactone oxidase, a key enzyme for ascorbic acid biosynthesis.

Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in this species. Pollock J.

Vitamin C biosynthesis in prosimians: Evidence for the anthropoid affinity of Tarsius. Birney E. Inability of bats to synthesise L-ascorbic acid. Milton K. Ascorbic acid content of neotropical plant parts available to wild monkeys and bats. Hampl J.

Public Health. Schleicher R. Rowe S. Villalpando S. Vitamins A, and C and folate status in Mexican children under 12 years and women 12—49 years: A probabilistic national survey. Salud Publica Mex.

Garcia O. Zinc, vitamin A, and vitamin C status are associated with leptin concentrations and obesity in Mexican women: Results from a cross-sectional study.

Cahill L. Vitamin C deficiency in a population of young Canadian adults. Ravindran R. Inverse association of vitamin C with cataract in older people in India. Nishikawa Y. Interconversion between dehydro-L-ascorbic acid and L-ascorbic acid. Dewhirst R. The oxidation of dehydroascorbic acid and 2,3-diketogulonate by distinct reactive oxygen species.

Sauberlich H. Pharmacology of vitamin C. Arrigoni O. Ascorbic acid: Much more than just an antioxidant. Pauling L. Ascorbic acid. Przybylo M. On the physiological and cellular homeostasis of ascorbate. Cell Mol. Rose R. Solubility properties of reduced and oxidized ascorbate as determinants of membrane permeation. Zhitkovich A. Nuclear and Cytoplasmic Functions of Vitamin C. Tsukaguchi H. Sotiriou S. Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival.

Subramanian V. Molecular mechanism s involved in differential expression of vitamin C transporters along the intestinal tract. Liver Physiol. Macias R. Hepatic expression of sodium-dependent vitamin C transporters: Ontogeny, subtissular distribution and effect of chronic liver diseases.

Larsson N. Identification of vitamin C transporters in the human airways: A cross-sectional in vivo study. BMJ Open. Wang Y. Santulli G. Nova Science Publishers, Inc. Portugal C. Caveolinmediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype. Ludke A.

Cell Physiol. Cho S. Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression. Malo C. Glucose modulates vitamin C transport in adult human small intestinal brush border membrane vesicles.

Nualart F. Cell Res. Vera J. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid. Corpe C. Dong W. Multiple genome analyses reveal key genes in Vitamin C and Vitamin D synthesis and transport pathways are shared. Lukawski M. Experimental evidence and physiological significance of the ascorbate passive diffusion through the lipid bilayer.

Pozzer D. Redox Signal. Nygaard G. IEEE Eng. Bozonet S. Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. Levine M. Vitamin C: A concentration-function approach yields pharmacology and therapeutic discoveries. Vitamin C pharmacokinetics in healthy volunteers: Evidence for a recommended dietary allowance.

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Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer. Cancer Chemother.

Bangham A. Asupan vitamin C dari suplemen dan multivitamin tidak dapat menggantikan asupannya dari makanan. Sebisa mungkin, cukupi asupan vitamin C dengan memperbanyak konsumsi buah-buahan yang mengandung vitamin C tinggi, contohnya jeruk, lemon, kiwi, mangga, pepaya, dan stroberi.

Asupan vitamin C alami juga bisa didapatkan dari beberapa sayuran yang mengandung banyak vitamin C, seperti brokoli, tomat, bayam, dan kubis. Simpan vitamin C di tempat yang kering, terhindar dari sinar matahari langsung, dan pada suhu ruangan. Jauhkan obat dari jangkauan anak-anak. Ada beberapa efek interaksi yang mungkin terjadi jika vitamin C digunakan bersama obat-obatan tertentu, yaitu:. Pada umumnya, vitamin C aman jika digunakan sesuai aturan pakai dan tidak melebihi dosis yang dianjurkan.



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